Nurofen Plus (codeine/ibuprofen) – MIMS – Serious clinical harms at higher than recommended doses
01/03/2023
Medicines for human use
Safety update
This article was produced by the HPRA for publication in the March edition of Monthly Index of Medical Specialties (MIMS) and describes serious clinical harms, including renal tubular acidosis and severe hypokalaemia, following prolonged use of codeine/ibuprofen at higher than recommended doses.