Advice for patients considering cell-based therapies

The use of blood or cells for stem cell transplants is well established. 

Cell-based therapies use blood or cells from either the patient or a donor to heal or fix something in the body. If the cells are used differently than in the donor or are substantially manipulated, they are not considered stem cell transplants and they must follow special rules to ensure safety. 

It’s important to be cautious with cell-based therapies because some treatments might not be properly tested and could be dangerous. 

Read advice from European expert committee

Experts from the European Medicines Agency’s Committee for Advanced Therapies (CAT) advise against using unproven treatments. The HPRA support this position. You can check the EMA website to get more information on cell-based therapies. If you have any doubts, you can ask for help by emailing info@hpra.ie.

Consult your healthcare team

Always discuss potential treatments with your healthcare team and prioritise treatment backed by scientific evidence from reputable sources. 

Be wary of online advertising of cell-based therapies

Providers of these new cell-based therapies are not permitted to promote them to the general public. Where cell-based therapies are advertised through websites and social media, the HPRA encourages anyone considering cell-based therapies to visit the link above and contact us at info@hpra.ie if you have any questions about a treatment’s regulatory status.

Carefully evaluate the company’s information 

Are they offering the same treatment for many conditions?

Be wary of broad claims. It’s unlikely one treatment can address multiple diseases affecting different areas of the body. Stem cells usually need to be specifically manipulated in a laboratory to target specific diseases/areas.

Are they advertising directly to patients and on social media?

Be cautious about direct advertising. Clinics advertising directly to patients might not be suitable and could be harmful. 

Are they using persuasive language?

Watch for misleading language. Unproven treatments often use persuasive language and false testimonials, lacking scientific evidence. Treatment discussions should always cover the risks and benefits of treatment. No treatment is 100% risk free.

Are they vague about their location?

Transparency is key. Legitimate clinics will clearly state their location and be able to state clearly who regulates them and authorises their activity.